Adenosine 5'-monophosphate | 61-19-8

Adenosine 5'-monophosphate (AMP) inonzi nucleotide inoumbwa neadenine, ribose, uye boka rimwechete rephosphate.

Mushonga Wemakemikari: AMP inotorwa kubva ku nucleoside adenosine, apo adenine inobatanidzwa ne ribose, uye rimwe boka re phosphate rinosungirirwa kune 5 'carbon ye ribose kuburikidza ne phosphoester bond.

Biological Basa: AMP chinhu chakakosha chenyucleic acids, inoshanda semonomer mukuvaka kweRNA mamorekuru. MuRNA, AMP inosanganisirwa mucheni yepolymer kuburikidza nephosphodiester bond, ichigadzira musana weRNA strand.

Energy Metabolism: AMP inobatanidzwawo mumasero emagetsi metabolism. Inoshanda seyakatangira adenosine diphosphate (ADP) uye adenosine triphosphate (ATP) kuburikidza ne phosphorylation reactions inogadziriswa nema enzymes akadai seadenylate kinase. ATP, kunyanya, ndiyo yekutanga simba inotakura mumaseru, ichipa simba kune akasiyana cellular maitiro.

Metabolic Regulation: AMP inobata basa mukugadzirisa masero emagetsi. Maserura AMP mazinga anogona kuchinjika mukupindura shanduko yemetabolism uye simba rekuda. Huwandu hweAMP hunoenderana neATP hunogona kumisa nzira dzemagetsi dzinonzwa, dzakadai seAMP-activated protein kinase (AMPK), iyo inodzora metabolism kuchengetedza simba homeostasis.

Dietary Source: AMP inogona kuwanikwa kubva kune zvekudya, kunyanya muzvokudya zvakapfuma nucleic acids, zvakadai senyama, hove, uye nyemba.

Pharmacological Applications: AMP uye zvinobva mairi zvakaongororwa kune zvingangove zvekurapa zvikumbiro. Semuyenzaniso, cAMP (cyclic AMP), yakabva kuAMP, inoshanda semutumwa wechipiri mukufamba kwechiratidzo nzira uye inonangwa nemishonga yakasiyana-siyana yekurapa mamiriro akaita seasima, kusagadzikana kwemoyo, uye kusaenzana kwehomoni.